Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod

Roles of TLR7 in Activation of NF-κB Signaling of Keratinocytes by Imiquimod

Imiquimod is known to exert its effects through Toll-like receptor 7 (TLR7) and/or TLR8, resulting in expression of proinflammatory cytokines and chemokines. Keratinocytes have not been reported to constitutively express TLR7 and TLR8, and the action of imiquimod is thought to be mediated by the ade...

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Bibliographic Details
Main Authors: Li, Zheng Jun, Sohn, Kyung-Cheol, Choi, Dae-Kyoung, Shi, Ge, Hong, Dongkyun, Lee, Han-Eul, Whang, Kyu Uang, Lee, Young Ho, Im, Myung, Lee, Young, Seo, Young-Joon, Kim, Chang Deok, Lee, Jeung-Hoon
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3795621/

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