Quantitative set analysis for gene expression: a method to quantify gene set differential expression including gene-gene correlations
Enrichment analysis of gene sets is a popular approach that provides a functional interpretation of genome-wide expression data. Existing tests are affected by inter-gene correlations, resulting in a high Type I error. The most widely used test, Gene Set Enrichment Analysis, relies on computationall...
Main Authors: | Yaari, Gur, Bolen, Christopher R., Thakar, Juilee, Kleinstein, Steven H. |
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Format: | Online |
Language: | English |
Published: |
Oxford University Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794608/ |
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