Truncated SSX Protein Suppresses Synovial Sarcoma Cell Proliferation by Inhibiting the Localization of SS18-SSX Fusion Protein

Synovial sarcoma is a relatively rare high-grade soft tissue sarcoma that often develops in the limbs of young people and induces the lung and the lymph node metastasis resulting in poor prognosis. In patients with synovial sarcoma, specific chromosomal translocation of t(X; 18) (p11.2;q11.2) is obs...

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Main Authors: Yoneda, Yasushi, Ito, Sachio, Kunisada, Toshiyuki, Morimoto, Yuki, Kanzaki, Hirotaka, Yoshida, Aki, Shimizu, Kenji, Ozaki, Toshifumi, Ouchida, Mamoru
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793959/