Peripartum Cardiomyopathy

Peripartum Cardiomyopathy

Peripartum cardiomyopathy (PPCM) is a rare form of unexplained cardiac failure of unknown origin, unique to the pregnant woman with highly variable outcome associated with high morbidity and mortality. PPCM is fraught with controversies in its definition, epidemiology, pathophysiology, diagnosis and...

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Main Authors: Okeke, TC, Ezenyeaku, CCT, Ikeako, LC
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793431/
id pubmed-3793431
recordtype oai_dc
spelling pubmed-37934312013-10-10 Peripartum Cardiomyopathy Okeke, TC Ezenyeaku, CCT Ikeako, LC Review Article Peripartum cardiomyopathy (PPCM) is a rare form of unexplained cardiac failure of unknown origin, unique to the pregnant woman with highly variable outcome associated with high morbidity and mortality. PPCM is fraught with controversies in its definition, epidemiology, pathophysiology, diagnosis and management. PPCM is frequently under diagnosed, inadequately treated and without a laid down follow-up regimen, thus, the aim of this review. Publications on PPCM were accessed using Medline, Google scholar and Pubmed databases. Relevant materials on PPCM, selected references from internet services, journals, textbooks, and lecture notes on PPCM were also accessed and critically reviewed. PPCM is multifactorial in origin. It is a diagnosis of exclusion and should be based on classic echocardiographic criteria. The outcome of PPCM is also highly variable with high morbidity and mortality rates. Future pregnancies are not recommended in women with persistent ventricular dysfunction because the heart cannot tolerate increased cardiovascular workload associated with the pregnancy. Although, multiparity is associated with PPCM, there is an increased risk of fetal prematurity and fetal loss. PPCM is a rare form of dilated cardiomyopathy of unknown origin, unique to pregnant women. The pathophysiology is poorly understood. Echocardiography is central to diagnosis of PPCM and effective treatment monitoring in patients of PPCM. The outcome is highly variable and related to reversal of ventricular dysfunction. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3793431/ /pubmed/24116305 http://dx.doi.org/10.4103/2141-9248.117925 Text en Copyright: © Annals of Medical and Health Sciences Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Okeke, TC
Ezenyeaku, CCT
Ikeako, LC
spellingShingle Okeke, TC
Ezenyeaku, CCT
Ikeako, LC
Peripartum Cardiomyopathy
author_facet Okeke, TC
Ezenyeaku, CCT
Ikeako, LC
author_sort Okeke, TC
title Peripartum Cardiomyopathy
title_short Peripartum Cardiomyopathy
title_full Peripartum Cardiomyopathy
title_fullStr Peripartum Cardiomyopathy
title_full_unstemmed Peripartum Cardiomyopathy
title_sort peripartum cardiomyopathy
description Peripartum cardiomyopathy (PPCM) is a rare form of unexplained cardiac failure of unknown origin, unique to the pregnant woman with highly variable outcome associated with high morbidity and mortality. PPCM is fraught with controversies in its definition, epidemiology, pathophysiology, diagnosis and management. PPCM is frequently under diagnosed, inadequately treated and without a laid down follow-up regimen, thus, the aim of this review. Publications on PPCM were accessed using Medline, Google scholar and Pubmed databases. Relevant materials on PPCM, selected references from internet services, journals, textbooks, and lecture notes on PPCM were also accessed and critically reviewed. PPCM is multifactorial in origin. It is a diagnosis of exclusion and should be based on classic echocardiographic criteria. The outcome of PPCM is also highly variable with high morbidity and mortality rates. Future pregnancies are not recommended in women with persistent ventricular dysfunction because the heart cannot tolerate increased cardiovascular workload associated with the pregnancy. Although, multiparity is associated with PPCM, there is an increased risk of fetal prematurity and fetal loss. PPCM is a rare form of dilated cardiomyopathy of unknown origin, unique to pregnant women. The pathophysiology is poorly understood. Echocardiography is central to diagnosis of PPCM and effective treatment monitoring in patients of PPCM. The outcome is highly variable and related to reversal of ventricular dysfunction.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793431/
_version_ 1612017184263897088

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