Mycobacterium tuberculosis and the host cell inflammasome: a complex relationship

The production of IL-1β during the infection with Mycobacterium tuberculosis (Mtb) is important for successful host immune defense. In macrophages and dendritic cells the host cell inflammasome is crucial for generation of secreted IL-1β in response to Mtb infections. In these cell types Mtb infecti...

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Bibliographic Details
Main Authors: Briken, Volker, Ahlbrand, Sarah E., Shah, Swati
Format: Online
Language:English
Published: Frontiers Media S.A. 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3793174/