Dual-degradable disulfide-containing PEI–Pluronic/DNA polyplexes: transfection efficiency and balancing protection and DNA release
Polymeric gene-delivery vectors to achieve lack of toxicity and a balance between protection and DNA release remains a formidable challenge. Incorporating intracellular environment-responsive degradable bonds is an appreciable step toward developing safer transfection agents. In this study, novel, d...
Main Authors: | , , |
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Format: | Online |
Language: | English |
Published: |
Dove Medical Press
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792845/ |