Generalized bacterial genome editing using mobile group II introns and Cre-lox

Generalized bacterial genome editing using mobile group II introns and Cre-lox

A general bacterial genome engineering framework, ‘Genome Editing via Targetrons and Recombinases' (GETR), is presented. GETR combines mobile group II introns (targetrons) and the Cre/lox system to allow genomic manipulations at a large scale.

Bibliographic Details
Main Authors: Enyeart, Peter J, Chirieleison, Steven M, Dao, Mai N, Perutka, Jiri, Quandt, Erik M, Yao, Jun, Whitt, Jacob T, Keatinge-Clay, Adrian T, Lambowitz, Alan M, Ellington, Andrew D
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792343/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792343/

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