Accurate LC Peak Boundary Detection for 16 O/ 18 O Labeled LC-MS Data

In liquid chromatography-mass spectrometry (LC-MS), parts of LC peaks are often corrupted by their co-eluting peptides, which results in increased quantification variance. In this paper, we propose to apply accurate LC peak boundary detection to remove the corrupted part of LC peaks. Accurate LC pea...

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Bibliographic Details
Main Authors: Cui, Jian, Petritis, Konstantinos, Tegeler, Tony, Petritis, Brianne, Ma, Xuepo, Jin, Yufang, Gao, Shou-Jiang (SJ), Zhang, Jianqiu (Michelle)
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3792097/