Synthesis and Characterization of Potential Dimers of Gatifloxacin – an Antibacterial Drug
Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, cha...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Österreichische Apotheker-Verlagsgesellschaft
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791930/ |
| Summary: | Gatifloxacin is an antibacterial agent belonging to the fourth-generation fluoroquinolone family. Four piperazine-linked fluoroquinolone dimers of Gatifloxacin were observed during the laboratory process for Gatifloxacin and they were identified. The present work describes the origin, synthesis, characterization, and control of these dimers along with the synthesis of Despropylene Gatifloxacin (metabolite). |
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