Astrocytes and glutamate homoeostasis in Alzheimer's disease: a decrease in glutamine synthetase, but not in glutamate transporter-1, in the prefrontal cortex

Astrocytes control tissue equilibrium and hence define the homoeostasis and function of the CNS (central nervous system). Being principal homoeostatic cells, astroglia are fundamental for various forms of neuropathology, including AD (Alzheimer's disease). AD is a progressive neurodegenerative...

Full description

Bibliographic Details
Main Authors: Kulijewicz-Nawrot, Magdalena, Syková, Eva, Chvátal, Alexander, Verkhratsky, Alexei, Rodríguez, José J.
Format: Online
Language:English
Published: American Society for Neurochemistry 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791522/