Podoplanin maintains high endothelial venule integrity by interacting with platelet CLEC-2

Circulating lymphocytes continuously enter lymph nodes (LNs) for immune surveillance through specialised blood vessels named high endothelial venules (HEVs)1–5, a process that increases dramatically during immune responses. How HEVs permit lymphocyte transmigration while maintaining vascular integri...

Full description

Bibliographic Details
Main Authors: Herzog, Brett H., Fu, Jianxin, Wilson, Stephen J., Hess, Paul R., Sen, Aslihan, McDaniel, J. Michael, Pan, Yanfang, Sheng, Minjia, Yago, Tadayuki, Silasi-Mansat, Robert, McGee, Samuel, May, Frauke, Nieswandt, Bernhard, Morris, Andrew J., Lupu, Florea, Coughlin, Shaun R., McEver, Rodger P., Chen, Hong, Kahn, Mark L., Xia, Lijun
Format: Online
Language:English
Published: 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3791160/