Stimulated nuclear import by β-like importins

Classic nuclear shuttling is mediated by an importin-α∙β heterodimer that binds to cargoes containing a nuclear localization signal, and shuttles most nuclear proteins immediately after their translation. Aside from this canonical mechanism, kariopheryn-βs or β-like importins operate by binding to n...

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Bibliographic Details
Main Authors: Flores, Karen, Seger, Rony
Format: Online
Language:English
Published: Faculty of 1000 Ltd 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790567/