Stimulated nuclear import by β-like importins
Classic nuclear shuttling is mediated by an importin-α∙β heterodimer that binds to cargoes containing a nuclear localization signal, and shuttles most nuclear proteins immediately after their translation. Aside from this canonical mechanism, kariopheryn-βs or β-like importins operate by binding to n...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Faculty of 1000 Ltd
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3790567/ |