Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling

Integrative genetic, epigenetic and pathological analysis of paraganglioma reveals complex dysregulation of NOTCH signaling

Head and neck paragangliomas, rare neoplasms of the paraganglia composed of nests of neurosecretory and glial cells embedded in vascular stroma, provide a remarkable example of organoid tumor architecture. To identify genes and pathways commonly deregulated in head and neck paraganglioma, we integra...

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Bibliographic Details
Main Authors: Cama, Alessandro, Verginelli, Fabio, Lotti, Lavinia Vittoria, Napolitano, Francesco, Morgano, Annalisa, D’Orazio, Andria, Vacca, Michele, Perconti, Silvia, Pepe, Felice, Romani, Federico, Vitullo, Francesca, di Lella, Filippo, Visone, Rosa, Mannelli, Massimo, Neumann, Hartmut P. H., Raiconi, Giancarlo, Paties, Carlo, Moschetta, Antonio, Tagliaferri, Roberto, Veronese, Angelo, Sanna, Mario, Mariani-Costantini, Renato
Format: Online
Language:English
Published: Springer Berlin Heidelberg 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789891/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789891/

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