The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells

Thyroid iodide accumulation via the sodium/iodide symporter (NIS; SLC5A5) has been the basis for the longtime use of radio-iodide in the diagnosis and treatment of thyroid cancers. NIS is also expressed, but poorly functional, in some non-thyroid human cancers. In particular, it is much more strongl...

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Bibliographic Details
Main Authors: Guerrieri, F, Piconese, S, Lacoste, C, Schinzari, V, Testoni, B, Valogne, Y, Gerbal-Chaloin, S, Samuel, D, Bréchot, C, Faivre, J, Levrero, M
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789165/