The sodium/iodide symporter NIS is a transcriptional target of the p53-family members in liver cancer cells
Thyroid iodide accumulation via the sodium/iodide symporter (NIS; SLC5A5) has been the basis for the longtime use of radio-iodide in the diagnosis and treatment of thyroid cancers. NIS is also expressed, but poorly functional, in some non-thyroid human cancers. In particular, it is much more strongl...
Main Authors: | , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789165/ |