Drug-primed reinstatement of cocaine seeking in mice: increased excitability of medium-sized spiny neurons in the nucleus accumbens

To examine the mechanisms of drug relapse, we first established a model for cocaine IVSA (intravenous self-administration) in mice, and subsequently examined electrophysiological alterations of MSNs (medium-sized spiny neurons) in the NAc (nucleus accumbens) before and after acute application of coc...

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Bibliographic Details
Main Authors: Ma, Yao-Ying, Henley, Sandy M., Toll, Jeff, Jentsch, James D., Evans, Christopher J., Levine, Michael S., Cepeda, Carlos
Format: Online
Language:English
Published: American Society for Neurochemistry 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789142/