Effect of in vivo administration of reprogramming factors in the mouse liver
Cancer is initiated by the transformation of stem cells or progenitor cells via a dedifferentiation process that leads to cancer stem cells; however, the process involves the activation of growth-promoting oncogenes and the inactivation of growth-constraining tumor suppressor genes. The introduction...
Main Authors: | , , , , , , , , , , , , , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
D.A. Spandidos
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789096/ |