Effect of in vivo administration of reprogramming factors in the mouse liver

Cancer is initiated by the transformation of stem cells or progenitor cells via a dedifferentiation process that leads to cancer stem cells; however, the process involves the activation of growth-promoting oncogenes and the inactivation of growth-constraining tumor suppressor genes. The introduction...

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Main Authors: TOMOKUNI, AKIRA, EGUCHI, HIDETOSHI, HOSHINO, HIROMITSU, DEWI, DYAH LAKSMI, NISHIKAWA, SHINPEI, KANO, YOSHIHIRO, MIYOSHI, NORIKATSU, TOJO, ARINOBU, KOBAYASHI, SEIICHIRO, GOTOH, NORIKO, HINOHARA, KUNIHIKO, FUSAKI, NOEMI, SAITO, TOSHIYUKI, SUEMIZU, HIROSHI, WADA, HIROSHI, KOBAYASHI, SHOGO, MARUBASHI, SHIGERU, TANEMURA, MASAHIRO, DOKI, YUICHIRO, MORI, MASAKI, ISHII, HIDESHI, NAGANO, HIROAKI
Format: Online
Language:English
Published: D.A. Spandidos 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789096/