Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis

Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of il...

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Main Authors:	Gupta, Vikas, Sharma, Anjani Kumar, Sureka, Rajendra Kumar, Bhuyan, Sushant Kumar, Singh, Prashant Kumar
Format:	Online
Language:	English
Published:	Medknow Publications & Media Pvt Ltd 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788296/

id	pubmed-3788296
recordtype	oai_dc
spelling	pubmed-37882962013-10-07 Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis Gupta, Vikas Sharma, Anjani Kumar Sureka, Rajendra Kumar Bhuyan, Sushant Kumar Singh, Prashant Kumar Case Report Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener's granulomatosis should be considered in the differential diagnosis of chronic meningitis. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3788296/ /pubmed/24101832 http://dx.doi.org/10.4103/0972-2327.116920 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Gupta, Vikas Sharma, Anjani Kumar Sureka, Rajendra Kumar Bhuyan, Sushant Kumar Singh, Prashant Kumar
spellingShingle	Gupta, Vikas Sharma, Anjani Kumar Sureka, Rajendra Kumar Bhuyan, Sushant Kumar Singh, Prashant Kumar Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis
author_facet	Gupta, Vikas Sharma, Anjani Kumar Sureka, Rajendra Kumar Bhuyan, Sushant Kumar Singh, Prashant Kumar
author_sort	Gupta, Vikas
title	Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis
title_short	Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis
title_full	Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis
title_fullStr	Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis
title_full_unstemmed	Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis
title_sort	chronic meningitis with multiple cranial neuropathies: a rare initial presentation of wegener's granulomatosis
description	Wegener's granulomatosis (WG) is a systemic necrotizing vasculitis that affects the small blood vessels. It mainly affects the upper and lower respiratory tract and kidneys. Central nervous system (CNS) involvement is rare, and has been reported only in about 8% of cases during the course of illness. Initial presentation with neurologic affection, particularly chronic hypertrophic meningitis is very unusual. We report the case of a 34 year old male who presented with chronic hypertrophic meningitis and multiple cranial nerve involvement as the initial manifestation, without respiratory and renal symptoms. This case highlights the difficulties in diagnosing a rare disease with rarer presentation, and at the same time illustrates that Wegener's granulomatosis should be considered in the differential diagnosis of chronic meningitis.
publisher	Medknow Publications & Media Pvt Ltd
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788296/
_version_	1612015682252177408

Chronic meningitis with multiple cranial neuropathies: A rare initial presentation of Wegener's granulomatosis

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