Proteolytic Processing of Von Willebrand Factor by Adamts13 and Leukocyte Proteases
ADAMTS13 is a 190 kDa zinc protease encoded by a gene located on chromosome 9q34. This protease specifically hydrolyzes von Willebrand factor (VWF) multimers, thus causing VWF size reduction. ADAMTS13 belongs to the A Disintegrin And Metalloprotease with ThromboSpondin type 1 repeats (ADAMTS) family...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Università Cattolica del Sacro Cuore
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787661/ |