Substance P participates in immune-mediated hepatic injury induced by concanavalin A in mice and stimulates cytokine synthesis in Kupffer cells
Studies have indicated that the immune system plays a pivotal role in hepatitis. Substance P (SP) has been shown to modulate the immune response. In order to investigate the role of SP in liver injury and to determine whether it leads to pro-inflammatory signaling, we established a mouse model of he...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
D.A. Spandidos
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786810/ |