Silver Nanoparticles and Mitochondrial Interaction

Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volu...

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Main Authors: Bressan, Eriberto, Ferroni, Letizia, Gardin, Chiara, Rigo, Chiara, Stocchero, Michele, Vindigni, Vincenzo, Cairns, Warren, Zavan, Barbara
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786470/
id pubmed-3786470
recordtype oai_dc
spelling pubmed-37864702013-10-07 Silver Nanoparticles and Mitochondrial Interaction Bressan, Eriberto Ferroni, Letizia Gardin, Chiara Rigo, Chiara Stocchero, Michele Vindigni, Vincenzo Cairns, Warren Zavan, Barbara Research Article Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volume ratio that leads to unique physical and chemical properties. So far, silver nanoparticles (AgNps) have been used in many more different medical devices than any other nanomaterial, mainly due to their antimicrobial properties. Despite the promising advantages posed by using AgNps in medical applications, the possible health effects associated with the inevitable human exposure to AgNps have raised concerns as to their use since a clear understanding of their specific interaction with biological systems has not been attained yet. In light of such consideration, aim of the present work is the morphological analysis of the intracellular behavior of AgNps with a diameter of 10 nm, with a special attention to their interaction with mitochondria. Hindawi Publishing Corporation 2013 2013-09-11 /pmc/articles/PMC3786470/ /pubmed/24101927 http://dx.doi.org/10.1155/2013/312747 Text en Copyright © 2013 Eriberto Bressan et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Bressan, Eriberto
Ferroni, Letizia
Gardin, Chiara
Rigo, Chiara
Stocchero, Michele
Vindigni, Vincenzo
Cairns, Warren
Zavan, Barbara
spellingShingle Bressan, Eriberto
Ferroni, Letizia
Gardin, Chiara
Rigo, Chiara
Stocchero, Michele
Vindigni, Vincenzo
Cairns, Warren
Zavan, Barbara
Silver Nanoparticles and Mitochondrial Interaction
author_facet Bressan, Eriberto
Ferroni, Letizia
Gardin, Chiara
Rigo, Chiara
Stocchero, Michele
Vindigni, Vincenzo
Cairns, Warren
Zavan, Barbara
author_sort Bressan, Eriberto
title Silver Nanoparticles and Mitochondrial Interaction
title_short Silver Nanoparticles and Mitochondrial Interaction
title_full Silver Nanoparticles and Mitochondrial Interaction
title_fullStr Silver Nanoparticles and Mitochondrial Interaction
title_full_unstemmed Silver Nanoparticles and Mitochondrial Interaction
title_sort silver nanoparticles and mitochondrial interaction
description Nanotechnology has gone through a period of rapid growth, thus leading to the constant increase in the application of engineered nanomaterials in daily life. Several different types of nanoparticles have been engineered to be employed in a wide array of applications due to their high surface to volume ratio that leads to unique physical and chemical properties. So far, silver nanoparticles (AgNps) have been used in many more different medical devices than any other nanomaterial, mainly due to their antimicrobial properties. Despite the promising advantages posed by using AgNps in medical applications, the possible health effects associated with the inevitable human exposure to AgNps have raised concerns as to their use since a clear understanding of their specific interaction with biological systems has not been attained yet. In light of such consideration, aim of the present work is the morphological analysis of the intracellular behavior of AgNps with a diameter of 10 nm, with a special attention to their interaction with mitochondria.
publisher Hindawi Publishing Corporation
publishDate 2013
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786470/
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