Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression
Proteins that interact with voltage-gated sodium (Nav) channels are important in channel sorting and modulation. In this study, we identified the transcriptional regulator, Sin3B, as a novel binding partner of Nav channels in a yeast two-hybrid screen and confirmed the interaction using pull-down as...
Main Authors: | , , |
---|---|
Format: | Online |
Language: | English |
Published: |
Nature Publishing Group
2013
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786298/ |