Interaction between the transcriptional corepressor Sin3B and voltage-gated sodium channels modulates functional channel expression

Proteins that interact with voltage-gated sodium (Nav) channels are important in channel sorting and modulation. In this study, we identified the transcriptional regulator, Sin3B, as a novel binding partner of Nav channels in a yeast two-hybrid screen and confirmed the interaction using pull-down as...

Full description

Bibliographic Details
Main Authors: Vega, Ana V., Avila, Guillermo, Matthews, Gary
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786298/