Novel CIC Point Mutations and an Exon-Spanning, Homozygous Deletion Identified in Oligodendroglial Tumors by a Comprehensive Genomic Approach Including Transcriptome Sequencing

Novel CIC Point Mutations and an Exon-Spanning, Homozygous Deletion Identified in Oligodendroglial Tumors by a Comprehensive Genomic Approach Including Transcriptome Sequencing

Oligodendroglial tumors form a distinct subgroup of gliomas, characterized by a better response to treatment and prolonged overall survival. Most oligodendrogliomas and also some oligoastrocytomas are characterized by a unique and typical unbalanced translocation, der(1,19), resulting in a 1p/19q co...

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Bibliographic Details
Main Authors: Eisenreich, Sophie, Abou-El-Ardat, Khalil, Szafranski, Karol, Campos Valenzuela, Jaime A., Rump, Andreas, Nigro, Janice M., Bjerkvig, Rolf, Gerlach, Eva-Maria, Hackmann, Karl, Schröck, Evelin, Krex, Dietmar, Kaderali, Lars, Schackert, Gabriele, Platzer, Matthias, Klink, Barbara
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785522/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785522/

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