Mouse Basophils Reside in Extracellular Matrix-Enriched Bone Marrow Niches Which Control Their Motility

Basophils co-express FcεRIα and CD49b, the α-2 chain of integrin-type receptor VLA-2 (α2β1), which recognizes type-1 collagen as a major natural ligand. The physiological relevance of this integrin for interactions with extracellular bone marrow matrix remains unknown. Herein, we examined the expres...

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Bibliographic Details
Main Authors: Smaniotto, Salete, Schneider, Elke, Goudin, Nicolas, Bricard-Rignault, Rachel, Machavoine, François, Dardenne, Mireille, Dy, Michel, Savino, Wilson
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3785469/