Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones

Protein kinase C activation decreases peripheral actin network density and increases central nonmuscle myosin II contractility in neuronal growth cones

PKC activation enhances myosin II contractility in the central growth cone domain while decreasing actin density and increasing actin network flow rates in the peripheral domain. This dual mode of action has mechanistic implications for interpreting reported effects of PKC on growth cone guidance an...

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Bibliographic Details
Main Authors: Yang, Qing, Zhang, Xiao-Feng, Van Goor, David, Dunn, Ashleigh P., Hyland, Callen, Medeiros, Nelson, Forscher, Paul
Format: Online
Language:English
Published: The American Society for Cell Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784383/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784383/

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