TrAp: a tree approach for fingerprinting subclonal tumor composition

Revealing the clonal composition of a single tumor is essential for identifying cell subpopulations with metastatic potential in primary tumors or with resistance to therapies in metastatic tumors. Sequencing technologies provide only an overview of the aggregate of numerous cells. Computational app...

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Bibliographic Details
Main Authors: Strino, Francesco, Parisi, Fabio, Micsinai, Mariann, Kluger, Yuval
Format: Online
Language:English
Published: Oxford University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783191/