Surgery-Related Thrombosis Critically Affects the Brain Infarct Volume in Mice Following Transient Middle Cerebral Artery Occlusion

Transient middle cerebral artery occlusion (tMCAO) model is widely used to mimic human focal ischemic stroke in order to study ischemia/reperfusion brain injury in rodents. In tMCAO model, intraluminal suture technique is widely used to achieve ischemia and reperfusion. However, variation of infarct...

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Bibliographic Details
Main Authors: Lin, Xiaojie, Miao, Peng, Wang, Jixian, Yuan, Falei, Guan, Yongjing, Tang, Yaohui, He, Xiaosong, Wang, Yongting, Yang, Guo-Yuan
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782513/