Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

Respiratory virus–induced EGFR activation suppresses IRF1-dependent interferon λ and antiviral defense in airway epithelium

Inhibition of epidermal growth factor receptor during viral infection augments IRF1-dependent IFN-λ production and decreases viral titers.

Bibliographic Details
Main Authors: Ueki, Iris F., Min-Oo, Gundula, Kalinowski, April, Ballon-Landa, Eric, Lanier, Lewis L., Nadel, Jay A., Koff, Jonathan L.
Format: Online
Language:English
Published: The Rockefeller University Press 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782052/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3782052/

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