Genotype Imputation Reference Panel Selection Using Maximal Phylogenetic Diversity
The recent dramatic cost reduction of next-generation sequencing technology enables investigators to assess most variants in the human genome to identify risk variants for complex diseases. However, sequencing large samples remains very expensive. For a study sample with existing genotype data, such...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Genetics Society of America
2013
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781962/ |