Anti-Aquaporin-1 Autoantibodies in Patients with Neuromyelitis Optica Spectrum Disorders
Autoantibodies against aquaporin-4 (AQP4), a water channel in CNS astrocytes, are detected in ∼50–80% of patients with neuromyelitis optica spectrum disorders (NMOsd), characterized by longitudinally extensive transverse myelitis (LETM) and/or optic neuritis. Although these autoantibodies present an...
Main Authors: | , , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3781161/ |