The Duration of Chlamydia muridarum Genital Tract Infection and Associated Chronic Pathological Changes Are Reduced in IL-17 Knockout Mice but Protection Is Not Increased Further by Immunization

The Duration of Chlamydia muridarum Genital Tract Infection and Associated Chronic Pathological Changes Are Reduced in IL-17 Knockout Mice but Protection Is Not Increased Further by Immunization

IL-17 is believed to be important for protection against extracellular pathogens, where clearance is dependent on neutrophil recruitment and local activation of epithelial cell defences. However, the role of IL-17 in protection against intracellular pathogens such as Chlamydia is less clear. We ha...

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Bibliographic Details
Main Authors: Andrew, Dean W., Cochrane, Melanie, Schripsema, Justin H., Ramsey, Kyle H., Dando, Samantha J., O’Meara, Connor P., Timms, Peter, Beagley, Kenneth W.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779189/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3779189/

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