Lipidomic profiling in Crohn's disease: Abnormalities in phosphatidylinositols, with preservation of ceramide, phosphatidylcholine and phosphatidylserine composition

Crohn's disease is a chronic inflammatory condition largely affecting the terminal ileum and large bowel. A contributing cause is the failure of an adequate acute inflammatory response as a result of impaired secretion of pro-inflammatory cytokines by macrophages. This defective secretion arise...

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Bibliographic Details
Main Authors: Sewell, Gavin W., Hannun, Yusuf A., Han, Xianlin, Koster, Grielof, Bielawski, Jacek, Goss, Victoria, Smith, Philip J., Rahman, Farooq Z., Vega, Roser, Bloom, Stuart L., Walker, Ann P., Postle, Anthony D., Segal, Anthony W.
Format: Online
Language:English
Published: Elsevier 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778899/