Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [18F]fluorodeoxyglucose positron emission tomography study☆

Catecholamine depletion in first-degree relatives of individuals with mood disorders: An [18F]fluorodeoxyglucose positron emission tomography study☆

Catecholamine depletion with alpha-methylparatyrosine (AMPT) has previously been shown to induce depressive symptoms in currently remitted patients with major depressive disorder (MDD) but not healthy controls. Thus sensitivity to catecholamine depletion has been hypothesized to be an endophenotype...

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Bibliographic Details
Main Authors: Savitz, Jonathan, Nugent, Allison C., Bellgowan, Patrick S.F., Wright, Niara, Tinsley, Ruth, Zarate, Carlos A., Herscovitch, Peter, Drevets, Wayne C.
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778263/

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