Reduced functional brain connectivity prior to and after disease onset in Huntington's disease☆☆☆

Reduced functional brain connectivity prior to and after disease onset in Huntington's disease☆☆☆

•We applied resting state fMRI in premanifest and manifest Huntington's disease.•Reduced functional brain connectivity was present in premanifest HD gene carriers.•Large regions demonstrate reduced functional brain connectivity in manifest HD.•Medial visual, default mode and executive control n...

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Bibliographic Details
Main Authors: Dumas, Eve M., van den Bogaard, Simon J.A., Hart, Ellen P., Soeter, Roelof P., van Buchem, Mark A., van der Grond, Jeroen, Rombouts, Serge A.R.B., Roos, Raymund A.C.
Format: Online
Language:English
Published: Elsevier 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778251/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3778251/

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