A Hybrid NRPS-PKS Gene Cluster Related to the Bleomycin Family of Antitumor Antibiotics in Alteromonas macleodii Strains

Although numerous marine bacteria are known to produce antibiotics via hybrid NRPS-PKS gene clusters, none have been previously described in an  Alteromonas  species. In this study, we describe in detail a novel hybrid NRPS-PKS cluster identified in the plasmid of the  Alteromonas macleodii stra...

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Bibliographic Details
Main Authors: Mizuno, Carolina Megumi, Kimes, Nikole E., López-Pérez, Mario, Ausó, Eva, Rodriguez-Valera, Francisco, Ghai, Rohit
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777966/