Unraveling Regulatory Programs for NF-kappaB, p53 and MicroRNAs in Head and Neck Squamous Cell Carcinoma

In head and neck squamous cell carcinoma (HNSCC), mutations of p53 usually coexist with aberrant activation of NF-kappaB (NF-κB), other transcription factors and microRNAs, which promote tumor pathogenesis. However, how these factors and microRNAs interact to globally modulate gene expression and me...

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Bibliographic Details
Main Authors: Yan, Bin, Li, Huai, Yang, Xinping, Shao, Jiaofang, Jang, Minyoung, Guan, Daogang, Zou, Sige, Van Waes, Carter, Chen, Zhong, Zhan, Ming
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777940/