The favorable impact of PIK3CA mutations on survival: an analysis of 2587 patients with breast cancer

The phosphatidylinositol-3 kinase (PI3K) pathway regulates a number of cellular processes, including cell survival, cell growth, and cell cycle progression. Consequently, this pathway is commonly deregulated in cancer. In particular, mutations in the gene PIK3CA that encodes the p110α catalytic subu...

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Bibliographic Details
Main Authors: Dumont, Amaury G., Dumont, Sarah N., Trent, Jonathan C.
Format: Online
Language:English
Published: Sun Yat-sen University Cancer Center 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777497/