Coordinated oscillations in cortical actin and Ca2+ correlate with cycles of vesicle secretion
The actin cortex both facilitates and hinders exocytosis of secretory granules. How cells consolidate these two opposing roles was not well understood. Here we show that antigen activation of mast cells induces oscillations in Ca2+ and PI(4,5)P2 lipids that in turn drive cyclic recruitment of N-WASP...
| Main Authors: | , |
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| Format: | Online |
| Language: | English |
| Published: |
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3777337/ |