Autoantibodies to Estrogen Receptor α in Systemic Sclerosis (SSc) as Pathogenetic Determinants and Markers of Progression

Systemic sclerosis (SSc) is a multisystem autoimmune disease of unknown etiology characterized by inflammation, autoantibody production, and fibrosis. It predominantly affects women, this suggesting that female sex hormones such as estrogens may play a role in disease pathogenesis. However, up to da...

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Bibliographic Details
Main Authors: Giovannetti, Antonello, Maselli, Angela, Colasanti, Tania, Rosato, Edoardo, Salsano, Felice, Pisarri, Simonetta, Mezzaroma, Ivano, Malorni, Walter, Ortona, Elena, Pierdominici, Marina
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776852/