Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis

Rare Variants in Calcium Homeostasis Modulator 1 (CALHM1) Found in Early Onset Alzheimer’s Disease Patients Alter Calcium Homeostasis

Calcium signaling in the brain is fundamental to the learning and memory process and there is evidence to suggest that its dysfunction is involved in the pathological pathways underlying Alzheimer’s disease (AD). Recently, the calcium hypothesis of AD has received support with the identification of...

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Bibliographic Details
Main Authors: Rubio-Moscardo, Fanny, Setó-Salvia, Núria, Pera, Marta, Bosch-Morató, Mònica, Plata, Cristina, Belbin, Olivia, Gené, Gemma, Dols-Icardo, Oriol, Ingelsson, Martin, Helisalmi, Seppo, Soininen, Hilkka, Hiltunen, Mikko, Giedraitis, Vilmantas, Lannfelt, Lars, Frank, Ana, Bullido, MªJesús, Combarros, Onofre, Sánchez-Juan, Pascual, Boada, Mercè, Tárraga, Lluís, Pastor, Pau, Pérez-Tur, Jordi, Baquero, Miquel, Molinuevo, José L., Sánchez-Valle, Raquel, Fuentes-Prior, Pablo, Fortea, Juan, Blesa, Rafael, Muñoz, Francisco J., Lleó, Alberto, Valverde, Miguel A., Clarimón, Jordi
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775809/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775809/

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