Hypoxia-inducible C-to-U coding RNA editing downregulates SDHB in monocytes
Background. RNA editing is a post-transcriptional regulatory mechanism that can alter the coding sequences of certain genes in response to physiological demands. We previously identified C-to-U RNA editing (C136U, R46X) which inactivates a small fraction of succinate dehydrogenase (SDH; mitochondria...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
PeerJ Inc.
2013
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775634/ |