Colorectal Cancers from Distinct Ancestral Populations Show Variations in BRAF Mutation Frequency

It has been demonstrated for some cancers that the frequency of somatic oncogenic mutations may vary in ancestral populations. To determine whether key driver alterations might occur at different frequencies in colorectal cancer, we applied a high-throughput genotyping platform (OncoMap) to query 38...

Full description

Bibliographic Details
Main Authors: Hanna, Megan C., Go, Christina, Roden, Christine, Jones, Robert T., Pochanard, Panisa, Javed, Ahmed Yasir, Javed, Awais, Mondal, Chandrani, Palescandolo, Emanuele, Van Hummelen, Paul, Hatton, Charles, Bass, Adam J., Chun, Sung Min, Na, Deuk Chae, Kim, Tae-Im, Jang, Se Jin, Osarogiagbon, Raymond U., Hahn, William C., Meyerson, Matthew, Garraway, Levi A., MacConaill, Laura E.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774610/