Recent positive selection of a human androgen receptor/ectodysplasin A2 receptor haplotype and its relationship to male pattern baldness

Genetic variants in the human androgen receptor gene (AR) are associated with male pattern baldness (androgenetic alopecia, AGA) in Europeans. Previous observations of long-range linkage disequilibrium at the AR locus are consistent with the hypothesis of recent positive selection. Here, we further...

Full description

Bibliographic Details
Main Authors: Hillmer, Axel M., Freudenberg, Jan, Myles, Sean, Herms, Stefan, Tang, Kun, Hughes, David A., Brockschmidt, Felix F., Ruan, Yijun, Stoneking, Mark, Nöthen, Markus M.
Format: Online
Language:English
Published: Springer-Verlag 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3774421/