JNK and NADPH Oxidase Involved in Fluoride-Induced Oxidative Stress in BV-2 Microglia Cells

Excessive fluoride may cause central nervous system (CNS) dysfunction, and oxidative stress is a recognized mode of action of fluoride toxicity. In CNS, activated microglial cells can release more reactive oxygen species (ROS), and NADPH oxidase (NOX) is the major enzyme for the production of extrac...

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Bibliographic Details
Main Authors: Yan, Ling, Liu, Shengnan, Wang, Chen, Wang, Fei, Song, Yingli, Yan, Nan, Xi, Shuhua, Liu, Ziyou, Sun, Guifan
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3773420/