Influence of COMT val158met Genotype on the Depressed Brain during Emotional Processing and Working Memory

Influence of COMT val158met Genotype on the Depressed Brain during Emotional Processing and Working Memory

Major depressive disorder (MDD) has been associated with abnormal prefrontal-limbic interactions and altered catecholaminergic neurotransmission. The val158met polymorphism on the catechol-O-methyltransferase (COMT) gene has been shown to influence prefrontal cortex (PFC) activation during both emot...

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Bibliographic Details
Main Authors: Opmeer, Esther M., Kortekaas, Rudie, van Tol, Marie-José, van der Wee, Nic J. A., Woudstra, Saskia, van Buchem, Mark A., Penninx, Brenda W., Veltman, Dick J., Aleman, André
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772077/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772077/

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