Mathematical Model for Radial Expansion and Conflation of Intratumoral Infectious Centers Predicts Curative Oncolytic Virotherapy Parameters

Mathematical Model for Radial Expansion and Conflation of Intratumoral Infectious Centers Predicts Curative Oncolytic Virotherapy Parameters

Simple, inductive mathematical models of oncolytic virotherapy are needed to guide protocol design and improve treatment outcomes. Analysis of plasmacytomas regressing after a single intravenous dose of oncolytic vesicular stomatitis virus in myeloma animal models revealed that intratumoral virus sp...

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Bibliographic Details
Main Authors: Bailey, Kent, Kirk, Amber, Naik, Shruthi, Nace, Rebecca, Steele, Michael B., Suksanpaisan, Lukkana, Li, Xing, Federspiel, Mark J., Peng, Kah-Whye, Kirk, David, Russell, Stephen J.
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770695/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770695/

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