In Vitro Screening for Compounds That Enhance Human L1 Mobilization

The Long interspersed element 1 (LINE1 or L1) retrotransposon constitutes 17% of the human genome. There are currently 80–100 human L1 elements that are thought to be active in any diploid human genome. These elements can mobilize into new locations of the genome, resulting in changes in genomic inf...

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Bibliographic Details
Main Authors: Terasaki, Natsuko, Goodier, John L., Cheung, Ling E., Wang, Yue J., Kajikawa, Masaki, Kazazian, Haig H., Okada, Norihiro
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770661/