Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction

Senescence is a recognized mechanism of cardiovascular diseases; however, its contribution to myocardial fibrosis and rupture after infarction and the underlying mechanisms remain unclear. Here we showed that senescent cardiac fibroblasts markedly accumulated in heart after myocardial infarction. Th...

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Bibliographic Details
Main Authors: Zhu, Fuli, Li, Yulin, Zhang, Junmeng, Piao, Chunmei, Liu, Tingting, Li, Hui-Hua, Du, Jie
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770549/