Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr−/− mice

Antisense oligonucleotide inhibition of cholesteryl ester transfer protein enhances RCT in hyperlipidemic, CETP transgenic, LDLr−/− mice

Due to their ability to promote positive effects across all of the lipoprotein classes, cholesteryl ester transfer protein (CETP) inhibitors are currently being developed as therapeutic agents for cardiovascular disease. In these studies, we compared an antisense oligonucleotide (ASO) inhibitor of C...

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Bibliographic Details
Main Authors: Bell, Thomas A., Graham, Mark J., Lee, Richard G., Mullick, Adam E., Fu, Wuxia, Norris, Dan, Crooke, Rosanne M.
Format: Online
Language:English
Published: The American Society for Biochemistry and Molecular Biology 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770078/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770078/

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