Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation

Memory is the capacity to store, maintain, and retrieve events or information from the mind. Difficulties in verbal episodic memory commonly occur in healthy aging. In this paper, we assess the hypothesis that anodal transcranial direct current stimulation (tDCS) applied over the dorsolateral prefro...

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Main Authors:	Manenti, Rosa, Brambilla, Michela, Petesi, Michela, Ferrari, Clarissa, Cotelli, Maria
Format:	Online
Language:	English
Published:	Frontiers Media S.A. 2013
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769624/

id	pubmed-3769624
recordtype	oai_dc
spelling	pubmed-37696242013-09-23 Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation Manenti, Rosa Brambilla, Michela Petesi, Michela Ferrari, Clarissa Cotelli, Maria Neuroscience Memory is the capacity to store, maintain, and retrieve events or information from the mind. Difficulties in verbal episodic memory commonly occur in healthy aging. In this paper, we assess the hypothesis that anodal transcranial direct current stimulation (tDCS) applied over the dorsolateral prefrontal cortex (DLPFC) or over the parietal cortex (PARC) could facilitate verbal episodic memory in a group of 32 healthy older adults and in a group of 32 young subjects relative to a sham stimulation using a single-blind randomized controlled design. Each participant underwent two sessions of anodal tDCS (left and right) and one session of sham stimulation. Overall, our results demonstrated that, in young and in older subjects, anodal tDCS applied during the retrieval phase facilitates verbal episodic memory. In particular, we found that tDCS applied over the left and right regions (DLPFC and PARC) induced better performance in young participants; only tDCS applied over the left regions (DLPFC and PARC) increased retrieval in older subjects. These results suggest that anodal tDCS can be a relevant tool to modulate the long-term episodic memory capacities of young and older subjects. Frontiers Media S.A. 2013-09-11 /pmc/articles/PMC3769624/ /pubmed/24062685 http://dx.doi.org/10.3389/fnagi.2013.00049 Text en Copyright © Manenti, Brambilla, Petesi, Ferrari and Cotelli. http://creativecommons.org/licenses/by/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Manenti, Rosa Brambilla, Michela Petesi, Michela Ferrari, Clarissa Cotelli, Maria
spellingShingle	Manenti, Rosa Brambilla, Michela Petesi, Michela Ferrari, Clarissa Cotelli, Maria Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation
author_facet	Manenti, Rosa Brambilla, Michela Petesi, Michela Ferrari, Clarissa Cotelli, Maria
author_sort	Manenti, Rosa
title	Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation
title_short	Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation
title_full	Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation
title_fullStr	Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation
title_full_unstemmed	Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation
title_sort	enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation
description	Memory is the capacity to store, maintain, and retrieve events or information from the mind. Difficulties in verbal episodic memory commonly occur in healthy aging. In this paper, we assess the hypothesis that anodal transcranial direct current stimulation (tDCS) applied over the dorsolateral prefrontal cortex (DLPFC) or over the parietal cortex (PARC) could facilitate verbal episodic memory in a group of 32 healthy older adults and in a group of 32 young subjects relative to a sham stimulation using a single-blind randomized controlled design. Each participant underwent two sessions of anodal tDCS (left and right) and one session of sham stimulation. Overall, our results demonstrated that, in young and in older subjects, anodal tDCS applied during the retrieval phase facilitates verbal episodic memory. In particular, we found that tDCS applied over the left and right regions (DLPFC and PARC) induced better performance in young participants; only tDCS applied over the left regions (DLPFC and PARC) increased retrieval in older subjects. These results suggest that anodal tDCS can be a relevant tool to modulate the long-term episodic memory capacities of young and older subjects.
publisher	Frontiers Media S.A.
publishDate	2013
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769624/
_version_	1612010751013158912

Enhancing verbal episodic memory in older and young subjects after non-invasive brain stimulation

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