Secreted and Transmembrane 1A Is a Novel Co-Stimulatory Ligand

Most T cell responses to pathogens or self antigens are modulated through the action of regulatory T cells and tissue-specific inhibitory mechanisms. To this end, several receptor-ligand pairs have evolved which either augment or diminish T cell function. Here we describe the tissue ligand SECTM1A (...

Full description

Bibliographic Details
Main Authors: Howie, Duncan, Garcia Rueda, Hugo, Brown, Marion H., Waldmann, Herman
Format: Online
Language:English
Published: Public Library of Science 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3769348/